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 maxferd pawn - maxpawn.com engineering of human CD4- (CD4-LV) and CD8-targeted vectors (CD8-LV) capable to deliver genes selectively into human CD4+ or CD8+ T cells (Zhou et al, 2012, 2015; Bender et al, 2016). Toward in situ generation of CAR T cells, here we report that CD19-reactive CD8+ CAR T cells can be generated in humanized mice upon a

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Background: It is unclear whether improvement in left ventricular (LV) ejection fraction (LVEF) following treatment with a combined α (1),β (1),β (2)-blockade can be attributed to improvement in LV contractility, to a reduction in afterload, and/or to improvements in LV remodeling and chamber size. We aimed to examine whether the observed .

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